Senior Research Associate at Personalis | Powderkeg

Personalis, Inc. is a leader in advanced cancer genomics for enabling the next generation of precision cancer therapies and diagnostics. The [Personalis NeXT Platform]( next-platform%2F&esheet=52534858&newsitemid=20211118006333&lan=en- US&anchor=Personalis+NeXT+Platform&index=2&md5=994af974cf5c973f890d0bc5a72ef63b)® is designed to adapt to the complex and evolving understanding of cancer, providing its biopharmaceutical customers and clinicians with information on all of the approximately 20,000 human genes, together with the immune system, from a single tissue sample. In population sequencing, Personalis operates one of the largest sequencing operations globally and is currently the sole sequencing provider to Veterans Affairs' Million Veteran Program. To enable cancer and population sequencing, Personalis' [Clinical Laboratory]( US&anchor=Clinical+Laboratory&index=3&md5=214191f02a8e211e8a6037256ce4a478) was built with a focus on clinical accuracy, quality, big data, scale and efficiency. The laboratory is GxP-aligned as well as Clinical Laboratory Improvement Amendments of 1988-certified and College of American Pathologists- accredited.

Summary: As a Senior Research Associate within the Technical Operations group, you will be part of a growing team to provide support and implement improvements to existing Next Generation Sequencing (NGS) based products and assist with transfer and validation of new processes and products into operations. The ideal candidate will have hands on experience with molecular biology techniques and familiarity working with high throughput lab information systems and robotic liquid handlers. You will be encouraged to think outside the box and creatively solve problems while collaborating with different groups across the organization.

**Responsibilities: **

  • __ Support the development, improvement and scale up of new and existing assays and transfer of new products into production.
  • Provide maintenance and day-to-day support to lab operations, including troubleshooting and addressing NCRs and CAPAs.
  • Collaborate with cross-functional teams to define lab process requirements for new products, as well as modifications to existing products.
  • Assist the LIMS team with deploying improvements and extensions to the existing Operations Informatics systems, as well as associated lab instruments and software systems.
  • Execute end to end testing and validation pertaining to Next Generation Sequencing assays and workflows.

**Requirements: **

  • B.S with 5 years of work experience in the life science industry.
  • M.S with 3 years of work experience in the life science industry.
  • Hands-on knowledge of molecular biology methods such as PCR, library preparation and enrichment for NGS, nucleic acid extraction, purification and quantification.
  • Experience with high throughput robotic liquid handlers.
  • Ability to draft clear SOPs, work instructions, protocols and validation reports.
  • Experience supporting lab information systems in a production environment.
  • Proven success working independently within a team, detail-oriented individual with the proven ability to think logically and innovatively toward problem solving.

_Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package. _


Job Summary
  • Job Title
    Senior Research Associate
  • Company
  • Location
    Menlo Park, CA
  • Employment Type
    Full time
Ready to apply?
Ready to apply?