Top BioTech Companies 2023 | Powderkeg
Top BioTech Companies

Top BioTech Companies

In 2023, biotech stands as a cornerstone of innovation, transforming healthcare through personalized medicine, advanced therapies, and disease eradication. It fuels sustainable agriculture, environmental conservation, and bio-based solutions, reaffirming its role in shaping a healthier, more resilient future.

Keep reading to learn who’s hiring, who’s trending, expert insights from executives in the BioTech industry, and more.

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Biotech Advances in the 21st Century

Before we hop into how biotechnology is shifting the way Americans work and live, let’s first define the oft-confused topic. Biotechnology is using biology and other sciences to make products that improve lives. Modern fields of science underneath the biotech umbrella include genomics, biomedical engineering and advanced immunology, a study largely in the limelight during the COVID-19 pandemic.

Biotechnology’s role in society has mostly been focused in research universities and hospitals. But, new regulations have made it easier for independent labs and corporations, in addition to accredited institutions, to research and innovate inside the biotech industry. These new changes have allowed for untapped innovation and talent to create new value and growth.

Marked by an increase in globalization and biotech companies’ stock, the private and public biotech industries continue to grow at a rapid pace. The United States east and west coasts have become hotbeds for medical innovation. With its access to a high-tech laborforce graduating from prestigious schools like Harvard, Boston College and Massachusetts Institute of Technology (MIT), Boston is leading the country and quite possible the world in biological transformation.

But, not far behind is the Unvalley and cities that don’t often get the spotlight that the Bay Area and Boston do for their biotechnological advancements.

As more growth is achieved, the largest biotech companies in the world together with small biotech companies in your neighborhood will continue to shape our society going forward.

And of course, top pharmaceutical companies – like Eli Lilly, Pfizer and others – also fit in with the world’s best biotech companies. During COVID-19, they rose to the occasion with extraordinary progress on vaccination in an unprecedented amount of time.

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Biotech in the Unvalley

The list of the world’s top biotech companies continues to change everyday with each new innovation and discovery. But, what doesn’t change is their contribution to the human race and society. The top 100 biotech companies are speckled across the United States, predominantly in talent hotspots like the Bay Area and Boston, as mentioned above. The top companies include Amgen, Gilead Sciences and Celgene.

However, the Unvalley has made significant progress on attracting and retaining talent, specifically in the biotech industry and related fields. Namely, Chicago is a magnet for biotechnology and pharmaceutical innovation in recent years. With such prestigious schools like Northwestern and University of Chicago graduating science experts, the Windy City is poised for even more growth into the future.

BioTech Companies That are Hiring

Check out these BioTech Startups that are currently hiring.
Healionics
Seattle - Healionics has applied its expertise in synthetic biomaterials to develop a novel vascular graft (artificial blood vessel) that, unlike existing grafts, remains open to blood flow long-term without need for costly interventions. Its first commercial application will be as a more reliable means of vascular access for dialysis patients, with a subsequent application to treat peripheral artery disease. We have great results in multiple controlled animal studies, a large patent portfolio, established production capacity, and are ready to begin human studies later this year in preparation for market launch. Near-Term Problem / Market Opportunity: Vascular Access for Dialysis Kidney failure patients need to have their blood filtered 3 times per week via dialysis. This removes waste from the blood, which would otherwise cause them to die. However, current methods for repeatedly accessing the bloodstream for dialysis are unreliable. This problem is a huge contributor to the $50 billion per year that the U.S. spends on dialysis patients (7% of Medicare’s entire budget!). A vascular graft is often implanted under the skin (connecting an artery to a vein) to create an access site with sufficient bloodflow for dialysis -- but existing grafts tend to occlude quickly, requiring repeated expensive interventions to keep them open. Solution: STARgraft Because our vascular graft remains open to blood flow much longer than existing grafts, it can potentially satisfy a severe unmet clinical need for ready-to-use, safe, long-term dialysis access, while substantially reducing costs, illness and death rate among dialysis patients. Product Pipeline We have additional products in development, including an implantable port which will allow needle-free dialysis. Eliminating the use of needles would further reduce cost and illness among dialysis patients, and allow them to perform dialysis in the convenience of their own home. In addition, our platform STAR biomaterial can improve the performance of a wide range of implantable devices via its remarkable ability to prevent both infection and scar tissue. We currently have two corporate-funded development contracts to explore STAR material’s use in multiple other device applications.
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Aurora
Pittsburgh - Cognition Therapeutics, Inc. is focused on the discovery and development of small molecule therapeutics targeting the toxic proteins that cause the cognitive decline associated with Alzheimer's disease and other degenerative diseases of the human brain. Toxic proteins play a crucial role in a large class of disease targets, and there are currently no therapeutics available to prevent toxic protein accumulation or block their destructive effects. Cognition is founded on the unique combination of biological expertise around these targets, including proprietary assays that emphasize functional responses and proprietary medicinal chemistry that insures novel, high quality small-molecule drug candidates.
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iCAD
Nashua - iCAD, Inc. (iCAD) is a provider of image analysis and workflow solutions that enable radiologists and other healthcare professionals to serve patients by identifying pathologies and pinpointing cancer earlier. iCAD offers a range of high-performance, expandable Computer-Aided Detection (CAD) systems and workflow solutions for mammography (film-based, digital radiography (DR) and computed radiography (CR), Magnetic Resonance Imaging (MRI), and Computed Tomography (CT)). iCAD's solutions aid in the early detection of the prevalent cancers including breast, prostate and colon cancer. The Company's CAD systems include algorithm and other technology together with standard computer and display equipment. CAD systems for the film-based analog mammography market also include a radiographic film digitizer, either manufactured by the Company or others for the digitization of film-based medical images. !
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Verve Therapeutics
Cambridge - Verve Therapeutics is a genetic medicines company pioneering a new approach to the care of cardiovascular disease, transforming treatment from chronic management to single-course gene editing medicines. The company’s initial two programs target PCSK9 and ANGPTL3, genes that have been extensively validated as targets for lowering blood lipids such as low-density lipoprotein cholesterol (LDL-C), a root cause of cardiovascular disease. Verve’s lead product candidate, VERVE-101, is designed to turn off the PCSK9 gene in the liver in order to disrupt blood PCSK9 protein production and thereby reduce blood LDL-C levels, with the goal of reducing a patient’s risk for cardiovascular disease. VERVE-101, currently in IND-enabling studies, is being developed initially for the treatment of patients with heterozygous familial hypercholesterolemia, a potentially fatal genetic heart disease.
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Scioto Biosciences
Indianapolis - Scioto Biosciences is a developer of Activated Bacterial Therapeutics (ABT) platform intended to deliver live bacteria to the gut. The company is developing innovative therapies devoted to having a transformative impact on the delivery of microbiome therapeutics, enabling medical practitioners to advance healing through microbiome therapeutics.
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Emulate
Boston - Emulate is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health. Our lab-ready Human Emulation System® includes three components: Zoë® Culture Module, Organ-Chips, and analytical software applications. The platform provides a window into the inner workings of human biology and disease—offering researchers a new technology designed to predict human response with greater precision and detail than conventional cell culture or animal-based experimental testing. Each of the Emulate proprietary Organ-Chip models—including the liver, intestine, and kidney—contains tiny hollow channels lined with tens of thousands of living human cells and tissues and is approximately the size of an AA battery. An Organ-Chip is a living, microengineered environment that recreates the natural physiology and mechanical forces that cells experience within the human body. Our founding team pioneered the Organs-on-Chips technology at the Wyss Institute for Biologically Inspired Engineering at Harvard University. Emulate holds the worldwide exclusive license from Harvard University to a robust and broad intellectual property portfolio for the Organs-on-Chips technology and related systems. For more information, please visit emulatebio.com.
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Opentrons Labworks
OpenTrons is a developer of a pipetting robot technology designed to automate experiments. The company's technology is automated laboratory equipment that automates experiments by using Python language, enabling scientific researchers to make the process faster and less tiresome.
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Unvalley Biotech Companies

Biotech has taken off in the Unvalley.

For example, Vanqua Bio is determined to solve neurodegeneration and Parkinson’s disease in the elder population. A relatively new startup to the biotech space, Vanqua raised $85 million in their Series B financing before launching their product to the public in the Summer of 2021. Want to work for a budding startup? There are plenty more where that came from.

In addition to Vanqua Bio, Abbvie is a leading biotechnology corporation based in Chicago. Abbvie is a biopharmaceutical company, combining the field of biology and pharmaceuticals. It’s a spinoff of another large corporation headquartered in Chicago, Abbott Laboratories.

Abbott is a multinational pharmaceutical company worth almost $40 billion. The makers of Pedialyte and similar health products, Abbott Labs was founded in Chicago over 140 years ago and has established itself as not only one of the American leaders in biotechnology but a global giant.

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Biotech in Indianapolis

If you’re looking for a job or company in a smaller metropolitan area, Indianapolis may be your best choice. The Circle City, aka Indianapolis, is home to two well-known biotech and pharmaceutical companies in Roche and Eli Lilly.

Founded in 1896 in Basel, Switzerland, Roche is a multinational research-based healthcare company and the largest pharmaceutical company in the world with a presence in all different regions of the world. Roche is the leading distributor of cancer treatments across the globe. In the United States Roche has a large office of folks in Indianapolis, Indiana.

Eli Lilly, on the other hand, primarily deals in pharmaceuticals. They make and distribute life-saving drugs like out of their downtown Indianapolis global headquarters. Eli Lilly is also known for its community initiatives via the Lilly Endowment, a $10 billion fund devoted to economic growth and development of the city’s citizens, arts, education and religious programs. Interested in an employer that supports social responsibility?

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Alchemy
We take films from idea to delivery. Conceptualizing, writing, casting, shooting, and editing – we do it all.

Biotech Boom in North Carolina

A metropolis in the Unvalley that dominates conversation in the biotechnology and pharmaceuticals industry is Raleigh-Durham, North Carolina. Another beneficiary of a strong reputation for education and intelligence, the Research Triangle surrounding Raleigh-Durham is home to Duke University, University of North Carolina and North Carolina State University, three very high-achieving colleges that churn out successful scientists and biotechnicians. Raleigh-Durham residents Brii BioSciences and Indigo Ag each raised more than $250 million in 2018 while Precision BioSciences raised a $110 million Series B round, contributing to a wave of innovation and talent hiring over the next few years.

Whether Chicago, Indianapolis or Raleigh-Durham catches your eye, you can’t go wrong in the Unvalley. No matter your desires in an employer, the AI-powered Powderkeg talent matching service can find your dream job at a biotech company in your preferred area.

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