Top BioTech Companies 2023 | Powderkeg
Top BioTech Companies

Top BioTech Companies

In 2023, biotech stands as a cornerstone of innovation, transforming healthcare through personalized medicine, advanced therapies, and disease eradication. It fuels sustainable agriculture, environmental conservation, and bio-based solutions, reaffirming its role in shaping a healthier, more resilient future.

Keep reading to learn who’s hiring, who’s trending, expert insights from executives in the BioTech industry, and more.

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Biotech Advances in the 21st Century

Before we hop into how biotechnology is shifting the way Americans work and live, let’s first define the oft-confused topic. Biotechnology is using biology and other sciences to make products that improve lives. Modern fields of science underneath the biotech umbrella include genomics, biomedical engineering and advanced immunology, a study largely in the limelight during the COVID-19 pandemic.

Biotechnology’s role in society has mostly been focused in research universities and hospitals. But, new regulations have made it easier for independent labs and corporations, in addition to accredited institutions, to research and innovate inside the biotech industry. These new changes have allowed for untapped innovation and talent to create new value and growth.

Marked by an increase in globalization and biotech companies’ stock, the private and public biotech industries continue to grow at a rapid pace. The United States east and west coasts have become hotbeds for medical innovation. With its access to a high-tech laborforce graduating from prestigious schools like Harvard, Boston College and Massachusetts Institute of Technology (MIT), Boston is leading the country and quite possible the world in biological transformation.

But, not far behind is the Unvalley and cities that don’t often get the spotlight that the Bay Area and Boston do for their biotechnological advancements.

As more growth is achieved, the largest biotech companies in the world together with small biotech companies in your neighborhood will continue to shape our society going forward.

And of course, top pharmaceutical companies – like Eli Lilly, Pfizer and others – also fit in with the world’s best biotech companies. During COVID-19, they rose to the occasion with extraordinary progress on vaccination in an unprecedented amount of time.

Jobs at Best BioTech Companies

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Biotech in the Unvalley

The list of the world’s top biotech companies continues to change everyday with each new innovation and discovery. But, what doesn’t change is their contribution to the human race and society. The top 100 biotech companies are speckled across the United States, predominantly in talent hotspots like the Bay Area and Boston, as mentioned above. The top companies include Amgen, Gilead Sciences and Celgene.

However, the Unvalley has made significant progress on attracting and retaining talent, specifically in the biotech industry and related fields. Namely, Chicago is a magnet for biotechnology and pharmaceutical innovation in recent years. With such prestigious schools like Northwestern and University of Chicago graduating science experts, the Windy City is poised for even more growth into the future.

BioTech Companies That are Hiring

Check out these BioTech Startups that are currently hiring.
Seven Bridges
Boston - Seven Bridges is the industry-leading unified bioinformatics solutions company accelerating precision medicine by enabling the understanding of biomedical data. Our platform, analytic tools, and services expertise are driving discovery and drug development at the world's leading academic, biotechnology, government, hospitals, and pharmaceutical entities. Through our collaboration with the largest genomics projects, we connect the world's biomedical information to enable the most efficient analysis at scale.
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Cardea Bio
San Diego - Cardea is developing a new generation of (bio)technology infrastructure based on proprietary biology-gated transistors. Cardean transistors leverage biocompatible graphene instead of silicon and replace optical signal observations with direct electrical molecular signal analysis. With Cardean transistors, the company and its Innovation Partners can generate streaming multi-omics data to measure real-time biological signals. Cardea is now manufacturing chips at scale and partners have started to significantly expand the amount, type, and quality of biological data they capture by building products that Conduct Biolog.
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VisionGate
Phoenix - VisionGate is dedicated to saving lives through early cancer detection and prevention, utilizing its revolutionary automated 3D cell imaging platform that is capable of generating high-resolution 3D biosignatures from intact cells. It is a clinical-stage oncology pharmaceutical and diagnostics company. Their lead diagnostic product is the LuCED lung test - a non-invasive sputum-based test that detects abnormal cells which indicate lung cancer and bronchial dysplasia. It was founded by Alan Nelson and is based in Phoenix, Arizona.
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Argonaut Manufacturing Services
Carlsbad - Your Contract Manufacturer for Life Sciences, Molecular Diagnostics, and Biopharmaceuticals.
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Scipher Medicine
Waltham - At Scipher Medicine, we are committed to transforming the way providers prescribe drugs, as well as the way manufacturers, develop new drugs. We have built a molecular map of all protein interactions that identifies genomic signatures and links those to disease and predictive treatment outcomes. Using a simple blood sample to analyze RNA, we can predict if a patient is likely to respond to a targeted therapy before therapy is prescribed. This insight allows patients to start the most effective therapy from day one. For our first commercial product, we have developed PrismRA®, a first-of-its-kind blood test that can predict which patients with rheumatoid arthritis are less likely to respond to TNFi therapies such as Humira® and Enbrel® so that such patients can go on alternative approved drugs. We also used a different one for the ACO Payer Summit, I’ve provided that as well: Scipher Medicine is building the future of patient treatment. Most patients who are prescribed blockbuster therapies today don't respond to treatment, costing the healthcare industry billions in wasted drugs while patients continue to suffer. Scipher's platform identifies which drug will work based on the patient's fundamental disease biology, and not based on symptoms, disease classification, or medical bias. A routine blood test predicts which drug he/she will respond to, with our first product focusing on rheumatoid arthritis, ensuring that the most optimal treatment is prescribed from day one. The molecular data generated by our tests is then used to fuel novel target discovery to address a clear unmet medical need in patients who do not respond to any existing therapy.
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Healionics
Seattle - Healionics has applied its expertise in synthetic biomaterials to develop a novel vascular graft (artificial blood vessel) that, unlike existing grafts, remains open to blood flow long-term without need for costly interventions. Its first commercial application will be as a more reliable means of vascular access for dialysis patients, with a subsequent application to treat peripheral artery disease. We have great results in multiple controlled animal studies, a large patent portfolio, established production capacity, and are ready to begin human studies later this year in preparation for market launch. Near-Term Problem / Market Opportunity: Vascular Access for Dialysis Kidney failure patients need to have their blood filtered 3 times per week via dialysis. This removes waste from the blood, which would otherwise cause them to die. However, current methods for repeatedly accessing the bloodstream for dialysis are unreliable. This problem is a huge contributor to the $50 billion per year that the U.S. spends on dialysis patients (7% of Medicare’s entire budget!). A vascular graft is often implanted under the skin (connecting an artery to a vein) to create an access site with sufficient bloodflow for dialysis -- but existing grafts tend to occlude quickly, requiring repeated expensive interventions to keep them open. Solution: STARgraft Because our vascular graft remains open to blood flow much longer than existing grafts, it can potentially satisfy a severe unmet clinical need for ready-to-use, safe, long-term dialysis access, while substantially reducing costs, illness and death rate among dialysis patients. Product Pipeline We have additional products in development, including an implantable port which will allow needle-free dialysis. Eliminating the use of needles would further reduce cost and illness among dialysis patients, and allow them to perform dialysis in the convenience of their own home. In addition, our platform STAR biomaterial can improve the performance of a wide range of implantable devices via its remarkable ability to prevent both infection and scar tissue. We currently have two corporate-funded development contracts to explore STAR material’s use in multiple other device applications.
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Aerin Medical
Sunnyvale - Aerin Medical is a health technology company that develops therapeutic devices to improve nasal breathing. Its device utilizes low-power radiofrequency energy to remodel nasal soft tissues and address the underlying cause of nasal congestion, enabling patients suffering from nasal breathing disorders to open their nasal airway quickly, safely, and effectively.
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Unvalley Biotech Companies

Biotech has taken off in the Unvalley.

For example, Vanqua Bio is determined to solve neurodegeneration and Parkinson’s disease in the elder population. A relatively new startup to the biotech space, Vanqua raised $85 million in their Series B financing before launching their product to the public in the Summer of 2021. Want to work for a budding startup? There are plenty more where that came from.

In addition to Vanqua Bio, Abbvie is a leading biotechnology corporation based in Chicago. Abbvie is a biopharmaceutical company, combining the field of biology and pharmaceuticals. It’s a spinoff of another large corporation headquartered in Chicago, Abbott Laboratories.

Abbott is a multinational pharmaceutical company worth almost $40 billion. The makers of Pedialyte and similar health products, Abbott Labs was founded in Chicago over 140 years ago and has established itself as not only one of the American leaders in biotechnology but a global giant.

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Biotech in Indianapolis

If you’re looking for a job or company in a smaller metropolitan area, Indianapolis may be your best choice. The Circle City, aka Indianapolis, is home to two well-known biotech and pharmaceutical companies in Roche and Eli Lilly.

Founded in 1896 in Basel, Switzerland, Roche is a multinational research-based healthcare company and the largest pharmaceutical company in the world with a presence in all different regions of the world. Roche is the leading distributor of cancer treatments across the globe. In the United States Roche has a large office of folks in Indianapolis, Indiana.

Eli Lilly, on the other hand, primarily deals in pharmaceuticals. They make and distribute life-saving drugs like out of their downtown Indianapolis global headquarters. Eli Lilly is also known for its community initiatives via the Lilly Endowment, a $10 billion fund devoted to economic growth and development of the city’s citizens, arts, education and religious programs. Interested in an employer that supports social responsibility?

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Biotech Boom in North Carolina

A metropolis in the Unvalley that dominates conversation in the biotechnology and pharmaceuticals industry is Raleigh-Durham, North Carolina. Another beneficiary of a strong reputation for education and intelligence, the Research Triangle surrounding Raleigh-Durham is home to Duke University, University of North Carolina and North Carolina State University, three very high-achieving colleges that churn out successful scientists and biotechnicians. Raleigh-Durham residents Brii BioSciences and Indigo Ag each raised more than $250 million in 2018 while Precision BioSciences raised a $110 million Series B round, contributing to a wave of innovation and talent hiring over the next few years.

Whether Chicago, Indianapolis or Raleigh-Durham catches your eye, you can’t go wrong in the Unvalley. No matter your desires in an employer, the AI-powered Powderkeg talent matching service can find your dream job at a biotech company in your preferred area.

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